2013年度 物質生命理工学科コロキウム

Old Dog with New Tricks (Clicks) -- Titanium(IV) in Anti-cancer Treatment
講師：Dr. Thomas Huhn (Konstanz University, Germany)

日時/場所	2014年 3月 25日（火） 15:30-17:00 （L-821・図書館内会議室）

詳細

　講師にDr. Thomas Huhn (Konstanz University, Germany) をお招きして、以下の内容でご講演いただきます。皆様お誘い合わせのうえご参加ください。
　＊申込不要・参加無料・学生、学外の方の聴講歓迎

"Old Dog with New Tricks (Clicks) -- Titanium(IV) in Anti-cancer Treatment"

With the introduction of cisplatin in anti-cancer treatment in the early 1970s the new area of inorganic-medicinal chemistry opened up for the inorganic chemist’s community. Many other metals have since been studied, many different ligand systems tested to identify suitable candidates for clinical studies. The field of titanium derived drugs has developed over the last 30 years from titanocenes to the recently introduced ONNO-type titanium-salan complexes. In this talk I will give a brief introduction to the theme, an overview over problems associated with and possible solutions towards the problem of premature hydrolysis of anti-cancer active Ti(IV) compounds. Finally, I will tell what type of ‘new clicks’ we taught our ‘old dogs’ recently.

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