2017年度 物質生命理工学科コロキウム
Synthesis as an Inspiration for Sustainability and Sensing
Prof. Steven Bull (University of Bath)
| 日時/場所 | 2017年8月29日（火）17:00-18:30 2-415 |
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詳細
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Synthesis as an Inspiration for Sustainability and Sensing
Prof. Steven Bull (University of Bath)
Catalysis for Sustainability: There is increasing awareness that society needs to develop more sustainable routes to fine chemicals, drugs and polymers that are currently sourced from non-renewable petroleum sources. Terpenes represent an abundant class of biorenewable natural products whose relatively non-oxygenated hydrocarbon skeletons contain alkene functionalities that are well suited as potential ‘drop-in’ substrates for existing industrial processes. We will demonstrate how catalytic transformations of terpenes such as limonene might be used to develop an industrial biorefinery approach for the synthesis of a range of value-added chemical products that are currently sourced from non-renewable petroleum sources.
Sensing for Healthcare: Our research into using boron compounds to develop simple three-component chiral derivatization protocol for determining the enantiopurity of chiral amines, diols, diamines, amino-alcohols and N-hydroxylamines using NMR spectroscopy, cyclic voltammetry or circular dichroism will be described. The development of boron based sensors for the colorometric detection of fluoride in water at environmentally relevant levels and the fluorescent detection of reactive oxygen species in clinically relevant scenarios will also be presented.
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