2014年度 物質生命理工学科コロキウム

Stereochemical Analysis of Natural Products and Related Compounds by Modern Chiroptical Methods
講師：Prof. Nina Berova (Columbia University, USA / 本学客員教授)

日時/場所	2014年 6月 2日（月） 16:30-18:00 （L-921・図書館内会議室）

詳細

　講師にProf. Nina Berova (Columbia University, USA / 本学客員教授) をお招きして、以下の内容でご講演いただきます。皆様お誘い合わせのうえご参加ください。
＊申込不要・参加無料・学生、学外の方の聴講歓迎

"Stereochemical Analysis of Natural Products and Related Compounds by Modern Chiroptical Methods"
Prof. Nina Berova (Columbia University, USA / 本学客員教授)

The recent technological advance in the chiroptical instrumentation for measurements of Optical Rotation (OR), Electronic Circular Dichroism (ECD), Vibrational Circular Dichroism (VCD) and the enormous progress in theoretical treatments of natural optical activity have not only stimulated the traditional research areas of structure determination and analysis with focus on chirality, but have also inspired new interdisciplinary studies.

For example, more recently the interest to chirality aspects in supramolecular systems, solute‐solvent interactions, molecular sensing and recognitions, and to concerted application of more than one chiroptical experimental method in combination with theoretical analysis have widespread to a greater variety of chemical structures of natural and synthetic origin. All these hot areas of research require now, more then before, interdisciplinary approaches involving the methods of organic, physical organic, bioorganic, inorganic and theoretical chemistry, as well as these of natural products and material sciences.

In this presentation we will discuss some examples on: chiral porphyrin based hostguest complexation; plasmonic enhancement of ECD in presence of silver nanoparticles and chiral supramolecular assemblies; combined application of chiroptical methods for determination of absolute configuration of few fungal metabolites. At the end we will discuss the recent determination of absolute configuration of synthetic 4a‐OH riboflavin analog, a key intermediate of FAD‐monooxygenate cycle.

本件に関するお問い合わせは、コロキウム委員（堀越、鈴木（伸））までお願いいたします。

ポスター1
ポスター2